Category Archives: News

Development of genomic assays for multi-arm clinical trials in cancer

There are an increasing number of molecular assays being developed to guide patient treatments. There is , however, often a limited amount of material available for analysis. Almac Diagnostics have therefore developed DNA and mRNA next generation sequencing based panels that have been analytically validated to deliver multiple Biomarkers from small amounts of material. An associated comprehensive patient report has been developed to guide the best treatment in oncology trials and eventually in standard clinical practice.

During his presentation at Pathology Horizons 2018 Prof. Kennedy will discuss the challenges to implementing these kind of Biomarker panels in clinical care and how these are being overcome.

Prof. Richard Kennedy is the Medical Director and Global VP of Biomarker Development at Almac Diagnostics and the McClay Professor in Medical Oncology at the Centre for Cancer Research and Cell Biology, Queen’s University of Belfast.

Why attend Pathology Horizons?

The conference is set to be another interesting and extremely informative event with a range of top international speakers demonstrating the power of new technologies, updates on procedural developments and valuable new lines of research – all in a relaxed and open atmosphere! Unlike other larger pathology events, Pathology Horizons is a boutique conference with one conference stream, which allows you to interact and network fully with the delegates and speakers. The conference is also CPD certified and has been awarded with 9 CPD credits by The Royal College of Pathologists.

Other topics from speakers include: 

  • Artificial intelligence and what it means for healthcare
  • Liquid biopsy and what it can do for detecting/treating ovarian cancer
  • Virtual and augmented reality in digital pathology
  • Radiology and pathology integration
  • Genome sequencing as a diagnostic aid

Don’t miss out, secure your place today!

Pathology Horizons 2018                                                                                    Lough Erne Resort, N. Ireland                                                                                        13-15th September

Prof. Levenson to give MUSE update at Pathology Horizons

MUSE (Microscopy with UV Surface Excitation), a novel, fast, simple Microscopy Method for slide-free histology continues to attract interest across the world. In fact, it made the front cover of BioPhotonics Magazine this month. Cirdan first brought Prof. Richard Levenson in to speak on this topic at Pathology Horizons in 2016. We are delighted to confirm that Prof. Levenson will be sharing the latest developments in MUSE at the upcoming Pathology Horizons conference in September.

Digital imaging of tissue slides is part of the future of anatomic pathology. However, as currently implemented, while facilitating logistics and enabling advanced analytical tools, it still requires the preparation of glass slides prior to scanning. An alternative strategy that bypasses conventional histological processing and its associated delays and expense would be useful, and a number of technologies for rapid, ex-vivo, slide-free microscopy are in research-and-development phase and a few have already been deployed as research-use-only commercial instruments. These contenders to replace FFPE-based histology appear promising for such uses as real-time surgical guidance, margin assessment, rapid on-site evaluation (ROSE), and potentially even for final tissue diagnosis, while accelerating care and decreasing costs. 

Prof. Levenson’s presentation entitled: “MUSE for Slide-Free, Real-Time Histology – It’s Cooler than Frozens.” will focus on MUSE and also look at a  few of these methods, including multiphoton and confocal microscopy, light-sheet microscopy, optical coherence tomography and structured illumination.

View. Prof. Levson’s bio

View Pathology Horizons 2018 Agenda

Register here for Early Bird

Dr. Kaplan talks Artificial Intelliegnce: What it Means for Healthcare and Pathology

Recent advances in Artificial Intelligence (AI) show great promise in several fields of medicine.  The field of deep learning is enabling the development of expert-level automated algorithms.

There are two aspects to consider when looking at the value in  using AI. First is the practical aspect. Use of AI can speed up the diagnostic process, ensuring diagnostic assessments are more reproducible. This helps physician productivity by automating some of the decision-making process.

The deeper aspect of AI’s impact is in its ability to analyze the data found. AI algorithms will begin to find patterns a human wouldn’t necessarily see, extending the capability of what physicians can do today. These advances could address the impact treatment of the disease has on outcomes.

AI is simply a tool – not a replacement for a pathologist. Deep learning can be applied to numerous diagnostic tasks and defines a new era in digital pathology.

Dr. Keith Kaplan, Chicago native and Publisher of leading industry blog tissuepathology.com will be discussing artificial intelligence, what it means for healthcare and pathology at the Pathology Horizons Conference this September in N.Ireland.

During his session  Dr. Kaplan will focus on advancements in AI in surgical pathology and what the use of this technology means for the future practice of pathology.

Objectives for this session:

  • Understand basic definitions in AI and deep learning.
  • Review applications and use cases to date within medicine and pathology
  • Discuss implications of AI for the practice of pathology
  • Highlight potential opportunities and weaknesses for AI within pathology

View Conference Agenda

Register now for Early Bird!

UCLA’s Dr. Wallace to speak on radiology and pathology integration at Pathology Horizons 2018

We are delighted to have Dr. Dean. W. Wallace, Professor of Pathology at the UCLA David Geffen School of Medicine in Los Angeles speak at Pathology Horizons 2018.

His talk at the conference ‘Opportunities Outweigh the Challenges of Radiology and Pathology Integration’ is an emerging area of discussion, and if implemented could help improve the overall quality of patient care. An abstract of Dr. Wallace’s talk will be released in the coming weeks and you will have the opportunity to hear his full presentation in September at the Lough Erne Resort in Northern Ireland.

More information on Dr. Wallace

Dr. Wallace is the chief of pulmonary and renal pathology services and is recognised as an expert in the fields of transplant pathology and lung cancer diagnostics. He is also the Director of the UCLA Telepathology and Digital Pathology Centre and co-led the team that created the innovative, first of its kind, Integrated Diagnostic Report (IDR) that combines multiple radiology and pathology studies into one dynamic reporting platform. Dr. Wallace has authored several dozen peer-reviewed papers and book chapters and was lead editor of a textbook in the field of transplant pathology.

About Pathology Horizons

 Pathology Horizons is an annual and open CPD conference organised by Cirdan to discuss what developments lie ahead in Pathology and what we can do to prepare or take advantage of these. Delegates will learn about new technologies, procedural developments and lines of research that are driving the future of pathology.

View conference agenda.

Places are limited, so please register early to avoid disappointment. Register for early bird now!

 

Hear from Dr. Buckley on the “Application of Liquid Biopsy to the Detection and Treatment of Ovarian Cancer”

We are delighted to welcome Dr. Niamh Buckley of Queen’s University Belfast to our panel of speakers for this year’s Pathology Horizons Conference in N. Ireland.

Dr. Buckley’s presentation, entitled: “Application of Liquid Biopsy to the Detection and Treatment of Ovarian Cancer” will focus on a project that she is currently working on.

About Dr. Buckley

Dr Niamh Buckley graduated from Trinity College, Dublin in 2002 with a First Class Honours Degree in Biochemistry.  She then carried out her Ph.D training in the Department of Oncology (Queen’s University Belfast) under the supervision of Prof. Paul Harkin.  Following this, she then worked as a post-doctoral researcher with Dr Paul Mullan in the Centre for Cancer Research and Cell Biology (Queen’s University Belfast).  During this time she investigated the role of the breast and ovarian tumour suppressor gene, BRCA1, in stem cell regulation and mammary gland differentiation.

Dr Buckley was awarded the prestigious Breast Cancer Now Fellowship in 2013 to develop novel biomarkers and therapeutic strategies in BRCA1-mutant and/or triple negative breast cancer.  In 2016 she was appointed as a Lecturer in Personalised Medicine and Pharmacogenomics in the School of Pharmacy (Queen’s University Belfast).  Her research focuses on the integration of in vitro, in vivo, bioinformatics and pathology approaches to identify key pathways underpinning poor outcome breast cancer and use detailed knowledge of this biology to identify appropriate targeted treatment options, personalising therapy in an area of unmet clinical need.

About Pathology Horizons

Pathology Horizons is an annual CPD conference focused on the future of pathology. Delegates will learn about new technologies, procedures and lines of research that are driving the future of pathology. This year the conference is being held in the five star Lough Erne Resort, Co. Fermanagh in N.Ireland from 13-15 September 2018.

View conference speakers and find out more  on how to register.

Early Bird Tickets now available.

Pathology Horizons is coming to N.Ireland

September 2018 will see Cirdan host the next Pathology Horizons conference in Northern Ireland for the first time ever.  Previous event locations have included Cairns and Fraser Island, Australia and Galway, Ireland. Pathology Horizons 2018 will be the fourth conference run by Cirdan and is to be held in the superb, five star Lough Erne Resort in County Fermanagh from 13 – 15 September.

Overview

Pathology Horizons is an annual CPD conference focused on the future of pathology and looking at what lies ahead in this area. The conference will attract expert speakers and delegates from all over the world.

Why attend?

This unique event will give delegates the chance to learn about new technologies, procedural developments and lines of research that are driving the future of pathology. They will hear about the pros and cons of these developments, how people in supporting disciplines should be preparing for and perhaps directing these changes and their potential impact on the daily work of a Pathologist.

Unlike many other events, Pathology Horizons is a boutique conference that provides an opportunity for delegates to contribute their ideas and interact with innovators from around the world, while expanding their knowledge and making some new contacts.

Who should attend?

The Pathology Horizons 2018 conference is open to anyone who is interested in the area of pathology e.g. Pathologists, Laboratory Managers and Biomedical Scientist.

Pathology Horizons 2017 Overview

The overview video of Pathology Horizons 2017 in Cairns will provide some insight into the conference content and give you a good feel for the event.

Get notified when Pathology Horizons 2018 conference registration opens.